David Wilson has kept his place on the bench for England's QBE International against South Africa on Saturday in a side showing six changes in all.
21-year-old lock Joe Launchbury has impressed off the bench against Fiji and Australia and is awarded with his first start for England.
Tom Wood (Northampton Saints) and Ben Morgan (Gloucester Rugby) take over from Tom Johnson and Thomas Waldrom at No 6 and 8 respectively, while Alex Corbisiero comes in for Joe Marler at loosehead prop.
Mike Brown (Harlequins) replaces Charlie Sharples on the left wing and Ben Youngs partners Leicester Tigers' team-mate Toby Flood at half-back.
There are also call-ups to the bench for the first time in this series for James Haskell, Mouritz Botha and Jonathan Joseph.
England Head Coach Stuart Lancaster said: "We have picked a team that will give us the best chance of beating South Africa. There were some tight calls, which is what you want as coaches, but the players we have brought into start have been training well, will bring a real motivation to make the most of their opportunity and will suit the challenge we face against a tough and physical South African team."
England (v South Africa, 2.30pm Saturday, Twickenham Stadium)
15. Alex Goode
14. Chris Ashton
13. Manusamoa Tuilagi
12. Brad Barritt
11. Mike Brown
10. Toby Flood
9. Ben Youngs
1. Alex Corbisiero
2. Tom Youngs
3. Dan Cole
4. Joe Launchbury
5. Geoff Parling
6. Tom Wood
7. Chris Robshaw
8. Ben Morgan
Replacements
16. David Paice
17. David Wilson
18. Mako Vunipola
19. Mouritz Botha
20 James Haskell
21. Danny Care
22. Owen Farrell
23. Jonathan Joseph
