Joe Cokanasiga, Charlie Ewels, and Sam Underhill have all been named in the England side to face Australia on Saturday at Twickenham stadium. (kick-off 15:00)
There are nine changes to the side that faced Japan last weekend with three positional switches.
Jamie George (Saracens) retains his place at hooker with props Ben Moon (Exeter Chiefs) and Kyle Sinckler (Harlequins) returning to the starting line-up.
Courtney Lawes (Northampton Saints) shifts from the backrow to the second row alongside Maro Itoje (Saracens). Sam Underhill (Bath Rugby) will start at openside flanker with Mark Wilson (Newcastle Falcons) moving to no 8 and Brad Shields (Wasps) returning to blindside flanker.
Co-captain Owen Farrell (Saracens) is named at fly half with Ben Te’o (Worcester Warriors) and Henry Slade (Exeter Chiefs) as the centre pairing.
Joe Cokanasiga (Bath Rugby) will play on the right wing with Jonny May (Leicester Tigers) named on the opposite side.
Manu Tuilagi (Leicester Tigers) has been passed fit to play and is named as a finisher. The Tigers centre last played for England in 2016. Nathan Hughes (Wasps) is also included on the bench following the conclusion of his suspension.
Co-captain Dylan Hartley (Northampton Saints) is in line to make a record 56th international appearance at Twickenham this weekend. He is currently level with Jason Leonard on 55 appearances at the home of England Rugby.
Eddie Jones said: “We’ve picked our best 23 for the Australia game. We know they have a unique style of attack so our ability to defend that is going to be important. We are continually working on our strengths which is our set piece and our defence and they are areas that are progressing nicely.
“I’m really happy with the direction we’re going in terms of the way we play the game. We are developing a unique style of rugby, which is English and the players are proud to play that way.
“The second part is the leadership of the team through the co-captaincy of Dylan Hartley and Owen Farrell has been outstanding. We have seen growth in the togetherness of the team and I think we’ve seen that in the spirit in which they’ve played.
“Australia, we know are a traditional rival and we enjoy the occasion of playing them at Twickenham. The spirit of the fans has been outstanding. I think the atmosphere during these Quilter Internationals has been the best atmosphere I’ve certainly experienced and we encourage the fans to be at their robust best at the weekend.”
England have won their last five games against Australia and four of the last five at Twickenham against the Wallabies.
England starting XV
15 Elliot Daly (Wasps, 24 caps)
14 Joe Cokanasiga (Bath Rugby, 1 cap)
13 Henry Slade (Exeter Chiefs, 16 caps)
12 Ben Te’o (Worcester Warriors, 15 caps)
11 Jonny May (Leicester Tigers, 39 caps)
10 Owen Farrell (Saracens, 64 caps) co-captain
9 Ben Youngs (Leicester Tigers, 79 caps)
1 Ben Moon (Exeter Chiefs, 3 caps)
2 Jamie George (Saracens, 31 caps)
3 Kyle Sinckler (Harlequins, 16 caps)
4 Maro Itoje (Saracens, 25 caps)
5 Courtney Lawes (Northampton Saints, 67 caps)
6 Brad Shields (Wasps, 4 caps)
7 Sam Underhill (Bath Rugby, 8 caps)
8 Mark Wilson (Newcastle Falcons, 7 caps)
16 Dylan Hartley (Northampton Saints, 96 caps) co-captain
17 Alec Hepburn (Exeter Chiefs, 5 caps)
18 Harry Williams (Exeter Chiefs, 14 caps)
19 Charlie Ewels (Bath Rugby, 9 caps)
20 Nathan Hughes (Wasps, 17 caps)
21 Richard Wigglesworth (Saracens, 32 caps)
22 George Ford (Leicester Tigers, 50 caps)
23 Manu Tuilagi (Leicester Tigers, 26 caps)