Bath Rugby second row Dominic Day will earn his first Test cap this Saturday in Cardiff, as Wales welcome Ireland to the Millennium Stadium (k.o. 14.30, live on BBC Wales).
Day, who was one of only two players to appear in every Premiership Rugby match last season, is one of three uncapped players in the starting line-up for Wales, alongside wing Eli Walker (Ospreys) and Ross Moriarty (Gloucester Rugby).
Scott Williams, Day's former teammate at Scarlets, will captain Wales against Ireland. The centre will become Wales' s 131st captain on his 30th Test appearance and will be joined in the centre by uncapped Tyler Morgan.
Wales Head Coach Warren Gatland has named a blend of youth and experience for his side's first warm-up game ahead of the Rugby World Cup.
Hallam Amos will win his second cap at full-back and will join Alex Cuthbert and Walker in the back-three.
There is huge experience at half-back with James Hook lining up alongside Mike Phillips who will make his 94th appearance for his country. In the front row, Ospreys prop Nicky Smith and Aaron Jarvis are joined by former regional team-mate Richard Hibbard.
Former Wales U19 and U21 forward Day will feature for the first time in the second row, packing down alongside Scarlets' Jake Ball. Moriarty is joined in the back row by vice-captain Justin Tipuric and Ospreys number eight Dan Baker.
After intense training camps in Switzerland and Doha, Gatland is looking forward to seeing his side take to the field on Saturday and grasping their opportunity.
"Saturday is a real opportunity for these players to put their hand up," he said. "We have been really impressed over the last few weeks, we have put the players under a lot of pressure and they have responded really well. Today is their opportunity to show what they can do on the international stage."
"We have the right blend of youth and experience and it's all about grasping the chance at this level. It's going to be a huge occasion, Ireland coming to town, a packed Millennium Stadium and players with everything to play for."
WALES TEAM TO PLAY IRELAND:
Hallam Amos (Newport Gwent Dragons), Alex Cuthbert (Cardiff Blues), * Tyler Morgan (Newport Gwent Dragons), Scott Williams (Scarlets, CAPT), * Eli Walker (Ospreys), James Hook (Gloucester Rugby), Mike Phillips (Racing Metro); Nicky Smith (Ospreys), Richard Hibbard (Gloucester), Aaron Jarvis (Ospreys), Jake Ball (Scarlets), *Dominic Day (Bath Rugby), * Ross Moriarty (Gloucester Rugby), Justin Tipuric (Ospreys, Vice-CAPT), Dan Baker (Ospreys).
Replacements: Rob Evans (Scarlets), Kristian Dacey (Cardiff Blues), Scott Andrews (Cardiff Blues), James King (Ospreys), Taulupe Faletau (Newport Gwent Dragons), Lloyd Williams (Cardiff Blues), Gareth Anscombe (Cardiff Blues), Matthew Morgan (Bristol Rugby)