Club hooker Rob Webber is named on the bench, as is fly-half George Ford. Burgess (Bath Rugby) takes over from Jonathan Joseph in midfield and partners Brad Barritt (Saracens), who moves to outside centre in place of the injured Bath player.

Owen Farrell (Saracens) starts at No 10, while Billy Vunipola (Saracens) comes in at No 8 for Ben Morgan (Gloucester Rugby) who is still struggling with a knee injury.

James Haskell (Wasps) and Alex Goode (Saracens) are both included in the 23 for the first time in RWC 2015, covering back row and back three respectively.

England Head Coach Stuart Lancaster said: "We have a lot of respect for the Wales coaching team and their players, they are a high quality side and I am sure it will some occasion on Saturday evening.

"The support at Twickenham last week was incredible with the crowd really getting behind us and we will need them again this week to lift the players against a tough Wales team."

England team to face Wales, Twickenham Stadium, 8pm BST, (Saturday 26th September, 2015)

15 Mike Brown (Harlequins, 40 caps)

14 Anthony Watson (Bath Rugby, 12 caps)

13 Brad Barritt (Saracens, 24 caps)

12 Sam Burgess (Bath Rugby, 3 caps)

11 Jonny May (Gloucester Rugby, 17 caps)

10 Owen Farrell (Saracens, 32 caps)

9 Ben Youngs (Leicester Tigers, 50 caps)

1 Joe Marler (Harlequins, 34 caps)

2 Tom Youngs (Leicester Tigers, 25 caps)

3 Dan Cole (Leicester Tigers, 53 caps)

4 Geoff Parling (Exeter Chiefs, 26 caps)

5 Courtney Lawes (Northampton Saints, 41 caps)

6 Tom Wood (Northampton Saints, 39 caps)

7 Chris Robshaw (capt, Harlequins, 40 caps)

8 Billy Vunipola (Saracens, 20 caps)

Replacements

16 Rob Webber (Bath Rugby, 14 caps)

17 Mako Vunipola (Saracens, 24 caps)

18 Kieran Brookes (Northampton Saints, 13 caps)

19 Joe Launchbury (Wasps, 25 caps)

20 James Haskell (Wasps, 60 caps)

21 Richard Wigglesworth (Saracens, 24 caps)

22 George Ford (Bath Rugby, 14 caps)

23 Alex Goode (Saracens, 18 caps)

Burgess and Watson start for England

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