Jacques du Toit will make his first Gallagher Premiership start when Bath Rugby welcome Sale Sharks to the Rec.
The South African hooker has featured twice in the league as a replacement and will wear the number two shirt for the first time on Friday night.
Prop Henry Thomas joins du Toit in the front row, replacing the injured Will Stuart at tighthead, while Charlie Ewels returns as captain in the second row alongside Will Spencer.
Back row duo Sam Underhill and Zach Mercer come back in at openside flanker and Number 8 respectively to complete the pack changes.
Bath will have fresh faces at half-back for Sale’s visit. Rhys Priestland, who scored last time out against Bristol Bears, is back at fly-half outside scrum-half Will Chudley.
On the bench, Academy graduate Tom Doughty will make his first Premiership appearance should he appear from the bench.
Bath Rugby side to play Sale Sharks
15. Tom de Glanville, 14. Anthony Watson, 13. Max Clark, 12. Cameron Redpath, 11. Will Muir, 10. Rhys Priestland, 9. Will Chudley; 1. Juan Schoeman, 2. Jacques du Toit, 3. Henry Thomas, 4. Will Spencer, 5. Charlie Ewels ©, 6. Josh Bayliss, 7. Sam Underhill, 8. Zach Mercer
16. Tom Doughty, 17. Jamie Bhatti, 18. Christian Judge, 19. Josh McNally, 20. Taulupe Faletau, 21. Ben Spencer, 22. Orlando Bailey, 23. Joe Cokanasiga
15. Simon Hammersley, 14. Byron McGuigan, 13. Sam James, 12. Sam Hill, 11. Marland Yarde, 10. AJ MacGinty, 9. Faf de Klerk; 1. Bevan Rodd, 2. Akker van der Merwe, 3. Coenie Oosthuizen, 4. James Phillips, 5. Jean-Pierre du Preez, 6. Cobus Wiese, 7. Tom Curry ©, 8. Jean-Luc du Preez
16. Curtis Langdon, 17. Ross Harrison, 18. James Harper, 19. Cameron Nield, 20. Ben Curry, 21. Raphael Quirke, 22. Kieran Wilkinson, 23. Connor Doherty